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阿昔洛韦治疗小儿水痘24例疗效观察
稿件作者:江月萍;顾仁月;
作者单位:江苏省镇江市润州区人民医院
中文摘要:目的:探讨阿昔洛韦对小儿水痘的临床疗效及安全性。方法:46例水痘患儿随机分为两组,治疗组24例用阿昔洛韦5 mg/(kg?次),每日4次口服;对照组22例用利巴韦林注射液10 mg/(kg?d),每日静脉滴注一次。疗程均为5 d,其他治疗方法相同。结果:治疗组热退及结痂时间较对照组缩短(P<0.05),差异有统计学意义,且两组治疗前后周围血白细胞和中性粒细胞比较差异无统计学意义(P>0.05)。结论:阿昔洛韦对小儿水痘有显著疗效,而且安全可靠。
关键字词:阿昔洛韦;水痘;儿童
研究领域:儿科呼吸系统疾病
图文分类:R511
基金支持:
稿件页码:
An Observation of Clinical Efficacy of Acyclovir in 24 Cases of Child Chickenpox
英文摘要:Objective: To explore the clinical efficiency and safety of acyclovir in treating child chickenpox. Methods: Forty six cases of chickenpox were randomly divided into two groups. The treatment group (n=24) were treated with acyclovir of 5 mg/kg orally four times a day while the control group (n=22) with ribavirin of 10 mg/(kg?d) intravenously, once a day with, a course of 5 days for both groups. And the other treatments were the same. Results: The time of fever withdrawal and the scab in the treatment group was shorter than that of the control one (P<0.05). The peripheral blood leukocytes and neutrophils showed no significant difference before and after the treatment in two groups (P>0.05). Conclusions: There is a significant effect, safe and reliable for acyclovir to chickenpox in children.
关键字词:Acyclovir; Chickenpox; Children